SIOG - ESMO: Education resources
Handbook of Cancer in the Senior Patient (ESMO/SIOG) - updated version
The European Society for Medical Oncology (ESMO) and the International Society for Geriatric Oncology (SIOG) developed this handbook in 2010, which was initiated by Dirk Schrijvers, Branko Zakotnik, Riccardo Audisio, Hendrik van Halteren, Arti Hurria, and the undersigned. This handbook is not only for Europeans. Cancer is a disease related to ageing, and the proportion of senior patients increases worldwide. While the proportion of persons beyond age 70 is still small in developing countries, their numerous population means that there are more “elderlies” in India than in Europe. More info
In 2015, the decision was made to start updating this content so as to bring you the latest developments on this important topic. While the original PDF is still available for download, please find below the updated content.
Table of Contents
Chapter 1 - Introduction
- Defining the Elderly
- Biology of Ageing and Changes in the Organ Function
- Changes in Cognition
- Cancer and Ageing
- Clinical Aspects
- Further Reading
Chapter 2 - Cancer epidemiology
- Introduction
- Population Demographics
- Cancer Demographics
- Society-Related Problems
- Conclusions and Further Reading
Chapter 3 - Evaluation of the senior cancer patient: Comprehensive Geriatric Assessment and screening tools for the elderly
- Introduction
- Short Screening Tools
- Comprehensive Geriatric Assessment
- Tools to Help Decision Making
- Conclusion and Further Reading
Chapter 4 - Frailty in the elderly
Chapter 5 - Surgical treatment
- Introduction
- Assessing Older Patients
- Surgical Resection
- Postoperative Care
- Tumour Biology
- Conclusion
- Further Reading
Chapter 6 - Radiotherapy in the elderly cancer patients
- Indications for Radiotherapy in the Elderly
- Side Effects of Radiotherapy in the Elderly (Acute and Late)
- Efficacy and Outcome of Radiotherapy in the Ageing
- Palliative Setting: Toxicity and Efficacy Ratio
- Curative Setting: Combinations of Chemotherapy and Radiotherapy
- Conclusions and Further Reading
Chapter 7 - Hormonal anti-cancer treatment in the senior cancer patient
Chapter 8 - Cytotoxic and targeted anti-cancer treatment in the senior cancer patient
Chapter 9 - Diffuse Large B-Cell Lymphoma in the elderly: R-CHOP or adapted strategy?
- Introduction
- Initial Clinical and Biological Evaluation of Patients and the Disease
- Treatment: First-Line Strategy
- Treatment: At Relapse
- Conclusions and Further Reading
Chapter 10 - Management of Chronic Myeloproliferative Neoplasia (MPN) in elderly patients
- Diagnosis and Classification of Myeloproliferative Disorders
- Treatment Strategies of Chronic Myeloid Leukaemia (CML) in the Senior Patient
- Treatment Strategies of Polythemia Vera (PV) in the Senior Patient
- Treatment Strategies of Essential Thrombocytosis (ET) in the Senior Patient
- Treatment Strategies of Primary Myelofibrosis (PMF) in the Senior Patient
- Conclusions and Further Reading
Chapter 11 - Myelodysplastic syndromes in the senior patient
- The Relevance of Myelodysplastic Syndromes in the Elderly
- Classification and Risk Scoring in MDS
- Age-Adjusted Models and Assessment in Elderly MDS Patient
- Treatment Options in Elderly MDS Patients
- Future Perspectives and Further Reading
Chapter 12 - Breast cancer in the senior patient
- Introduction
- Early Breast Cancer
- Locally Advanced Breast Cancer
- Metastatic Breast Cancer
- Conclusion and Further Reading
Chapter 13 - Lung cancer in the elderly
- Introduction
- Early Non-Small-Cell Lung Cancer in the Elderly
- Advanced Non-Small-Cell Lung Cancer in the Elderly
- Small-Cell Lung Cancer in the Elderly
- Palliative Treatment in Elderly Lung Cancer Patients
- Conclusion and Further Reading
Chapter 14 - Treatment of colorectal cancer in the senior patient
Chapter 15 - Prostate cancer
- Introduction and General Background
- Epidemiology
- Diagnosis and Staging
- Prognosis
- Treatment
- Conclusion and Further Reading
Chapter 16 - Bladder cancer in the elderly
- Incidence and Mortality
- Aetiology and Risk Factors
- Pathology
- Natural History and Tumour Biology
- Signs and Symptoms
- Imaging, Cystoscopy, and Urinary Cytopathology
- Staging
- Treatment of Bladder Cancer
- Further Reading
Chapter 17 - Gynaecological cancer in the senior patient
- Introduction
- Cervical Cancer
- Uterine Cancer
- Special Types of Endometrial Malignancy
- Vaginal Cancer
- Vulvar Cancer
- Ovarian Cancer, Fallopian Tube Cancer, and Primary Peritoneal Cancer
- Conclusion and Further Reading
Chapter 18 - Head and neck cancer in the elderly
- Introduction
- Surgery
- Radiotherapy
- Chemoradiation
- Chemotherapy and Targeted Therapies
- Geriatric Assessment
- Conclusions and Further Reading
Chapter 19 - Renal Cell Cancer
- Introduction
- Surgery in the Senior Cancer Patient
- Systemic Therapy of Metastatic Renal Cell Carcinoma in the Senior Cancer Patient
- Patient-Focused Approach
- Conclusion and Further Reading