Laura Biganzoli, Nicolò Matteo Luca Battisti, Hans Wildiers, Amelia McCartney, Giuseppe Colloca, Ian H Kunkler, Maria-João Cardoso, Kwok-Leung Cheung, Nienke Aafke de Glas, Rubina M Trimboli, Beatriz Korc-Grodzicki, Enrique Soto-Perez-de-Celis, Antonio Ponti, Janice Tsang, Lorenza Marotti, Karen Benn, Matti S Aapro, Etienne G C Brain. Lancet Oncol. 2021 Jul;22(7):e327-e340. doi: 10.1016/S1470-2045(20)30741-5. Epub 2021 May 14.
SIOG Guidelines
SIOG Clinical Practice Guidelines are intended to provide the user with a set of recommendations for the best standards of cancer care in the elderly, based on the findings of evidence-based medicine. Published SIOG Guidelines are available on the following topics:
- Colorectal Cancer in the Elderly
- Prostate Cancer in the Elderly
- Diffuse Large Cell B-Cell Lymphoma
- Cardio toxicity in the Elderly
- Comprehensive Geriatric Assessment
- Radiation Therapy in the Elderly
- Nutrition
- Nursing
- Bladder Cancer in the Elderly
- COVID-19
Guidelines under development
- Acute Myeloid Leukemia (AML)
- Study to estimate the toxicity, dose-intensity, and benefit of anti-EGFR-based treatment in patients with advanced colon cancer according to age
- Corticosteroid therapy in the elderly cancer patient: Expert recommendations from SIOG
- Treatment of Ovarian cancer in older adults - Development of treatment algorithms and educational programs
- Update on the management of prostate cancer in older cancer patients
- CGA interventions in older patients with cancer
Published guidelines
July 22, 2021
SIOG COVID-19 Working Group
March 7, 2021
Anna Rachelle Mislang, Enrique Soto-Perez-de-Celis, Chiara Russo, Giuseppe Colloca, Grant R Williams, Shane O'Hanlon, Lisa Cooper, Anita O'Donovan, Riccardo A Audisio, Kwok-Leung Cheung, Regina Gironés Sarrió, Reinhard Stauder, Michael Jaklitsch, Clarito Cairo, Luiz Antonio Gil Jr, Schroder Sattar, Kumud Kantilal, Kah Poh Loh, Stuart M Lichtman, Etienne Brain, Hans Wildiers, Ravindran Kanesvaran, Nicolò Matteo Luca Battist. J Geriatr Oncol . 2021 Mar 5;S1879-4068(21)00057-6. doi: 10.1016/j.jgo.2021.03.003. Online ahead of print.
SIOG COVID-19 Working Group
July 27, 2020
Nicolò Matteo Luca Battisti, Anna Rachelle Mislang, Lisa Cooper, Anita O'Donovan, Riccardo A. Audisio, Kwok-Leung Cheung, Regina Gironés Sarrió, Reinhard Stauder, Enrique Soto-Perez-de-Celis, Michael Jaklitsch, Grant R. Williams, Shane O'Hanlon, Mahmood Alam,m Clarito Cairo, Giuseppe Colloca, Luiz Antonio Gil Jr, Schroder Sattar, Kumud Kantilal, Chiara Russo, Stuart M. Lichtman, Etienne Brain, Ravindran Kanesvaran, and Hans Wildiers. J Geriatr Oncol. 2020 Jul 16 doi: 10.1016/j.jgo.2020.07.008
APL task force
April 20, 2020
Klepin HD, Neuendorff NR, Larson RA, Hamaker ME, Breccia M, Montesinos P, Cordoba R. J Geriatr Oncol. 2020 Apr 6. pii: S1879-4068(19)30497-7. doi: 10.1016/j.jgo.2020.03.019.
February 10, 2020
Nicolas Mottet, Maria J Ribal, Helen Boyle, Maria De Santis, Philippe Caillet, Ananya Choudhury, Tullika Garg, Matthew Nielsen, Patrick Wüthrich, Kilian M Gust, Shahrokh F Shariat, Georgios Gakis. J Geriatr Oncol. 2020 Feb 10;S1879-4068(19)30481-3. doi: 10.1016/j.jgo.2020.02.001.
HER2 task force
July 10, 2019
Brain E, Caillet P, de Glas N, Biganzoli L, Cheng K, Lago LD, Wildiers H. J Geriatr Oncol. 2019 Jun 21. pii: S1879-4068(18)30479-X. doi: 10.1016/j.jgo.2019.06.004.
Prostate task force
July 9, 2019
Boyle HJ, Alibhai S, Decoster L, Efstathiou E, Fizazi K, Mottet N, Oudard S, Payne H, Prentice M, Puts M, Aapro M, Droz JP. Eur J Cancer. 2019 Jul;116:116-136. doi: 10.1016/j.ejca.2019.04.031. Epub 2019 Jun 10.
Surgical task force
October 1, 2018
Personalized management of elderly patients with rectal cancer: Expert recommendations of the European Society of Surgical Oncology, European Society of Coloproctology, International Society of Geriatric Oncology, and American College of Surgeons Commission on Cancer. Montroni I, Ugolini G, Saur NM, Spinelli A, Rostoft S, Millan M, Wolthuis A, Daniels IR, Hompes R, Penna M, Fürst A, Papamichael D, Desai AM, Cascinu S, Gèrard JP, Myint AS, Lemmens VEPP, Berho M, Lawler M, De Liguori Carino N, Potenti F, Nanni O, Altini M, Beets G, Rutten H, Winchester D, Wexner SD, Audisio RA. Eur J Surg Oncol. 2018 Aug 15. pii: S0748-7983(18)31272-1. doi: 10.1016/j.ejso.2018.08.003. [Epub ahead of print]
Quality of Life task force
July 18, 2018
Scotté F, Bossi P, Carola E, Cudennec T, Dielenseger P, Gomes F, Knox S, Strasser F. Ann Oncol. 2018 Jul 13. doi: 10.1093/annonc/mdy228. [Epub ahead of print]
Kidney task force
June 1, 2018
Ravindran Kanesvaran, Olivia Le Saux, Robert Motzer, Toni K Choueiri, Florian Scotté, Joaquim Bellmunt, Vincent Launay-Vacher. Lancet Oncol. 2018 Jun;19(6):e317-e326. doi: 10.1016/S1470-2045(18)30125-6. Epub 2018 Jun 1.
Nutrition task force
February 8, 2018
Mislang AR, Di Donato S, Hubbard J, Krishna L, Mottino G, Bozzetti F, Biganzoli L. J Geriatr Oncol. 2018 Jan 22. pii: S1879-4068(18)30014-6. doi: 10.1016/j.jgo.2018.01.003. [Epub ahead of print] .
Adherence task force
May 30, 2017
Mislang AR, Wildes TM, Kanesvaran R, Baldini C, Holmes HM, Nightingale G, Coolbrandt A, Biganzoli L. Cancer Treat Rev. 2017 Jun;57:58-66. doi: 10.1016/j.ctrv.2017.05.002. Epub 2017 May 15.
Radiopharmaceutical task force
April 7, 2017
John O. Prior, Silke Gillessen, Manfred Wirth, William Dale, Matti Aapro, Wim J.G. Oyen. European Journal of Cancer, Volume 77, May 2017
Prostate task force
January 13, 2017
Jean-Pierre Droz, Gilles Albrand, Silke Gillessen, Simon Hughes, Nicolas Mottet, Stéphane Oudard, Heather Payne, Martine Puts, Gilbert Zulian, Lodovico Balducci, Matti Aapro. European Urology Available online 11 January 2017
CLL task force
November 8, 2016
Stauder R, Eichhorst B, Hamaker M, Kaplanov K, Morrison V, Österborg A, Poddubnaya I, Woyach JA, Shanafelt T, Smolej L, Ysebaert L, Goede V. Ann Oncol. 2016 Nov 1. pii: mdw547. [Epub ahead of print]
Bone Health task force
December 1, 2016
J.J. Body, E. Terpos, B. Tombal, P. Hadji, A. Arif, A. Young, M. Aapro, R. Coleman. Cancer Treatment Reviews Available online 27 October 2016 In Press
March 8, 2016
Peggy S. Burhenn, Alexandra L. McCarthy, Aaron Begue, Ginah Nightingale, Karis Cheng, Cindy Kenis. J Geriatr Oncol. 2016 Sep;7(5):315-24. doi: 10.1016/j.jgo.2016.02.006. Epub 2016 Mar 5.
Taxanes task force
January 26, 2016
L. Biganzoli, M. Aapro, Sibylle Loibl, Hans Wildiers, Etienne Brain. Cancer Treatment Reviews February 2016 Volume 43, Pages 19–26
Surgical task force
December 17, 2015
Ghignone F, van Leeuwen BL, Montroni I, Huisman MG, Somasundar P, Cheung KL, Audisio RA, Ugolini G; International Society of Geriatric Oncology (SIOG) Surgical Task Force. Eur J Surg Oncol. 2015 Dec 17. pii: S0748-7983(15)00903-8. doi: 10.1016/j.ejso.2015.12.004. [Epub ahead of print]
Oral Chemotherapy
September 1, 2015
L. Biganzoli, S. Lichtman , J.-P. Michel , D. Papamichael , E. Quoix , C. Walko , M. Aapro. European Journal of Cancer 2015 Nov;51(17):2491-500. doi: 10.1016/j.ejca.2015.08.005. Epub 2015 Sep 1.
Diffuse large B-cell lymphoma
March 13, 2015
Morrison VA, Hamlin P, Soubeyran P, Stauder R, Wadhwa P, Aapro M, Lichtman S. J Geriatr Oncol. 2015 Mar;6(2):141-52. doi: 10.1016/j.jgo.2014.11.004. Epub 2014 Dec 7
Comprehensive Geriatric Assessment
July 28, 2014
Wildiers H, Heeren P, Puts M, Topinkova E, Janssen-Heijnen ML, Extermann M, Falandry C, Artz A, Brain E, Colloca G, Flamaing J, Karnakis T, Kenis C, Audisio RA, Mohile S, Repetto L, Van Leeuwen B, Milisen K, Hurria A. The J Clin Oncol. 2014 Aug 20;32(24):2595-603.
Colorectal Cancer in the Elderly TF
July 11, 2014
D. Papamichael, R. A. Audisio, B. Glimelius, A. de Gramont, R. Glynne-Jones, D. Haller, C.-H. Köhne, S. Rostoft, V. Lemmens, E. Mitry, H. Rutten, D. Sargent, J. Sastre, M. Seymour, N. Starling, E. Van Cutsem & M. Aapro. Ann Oncol. 2015 Mar;26(3):463-76. doi: 10.1093/annonc/mdu253. Epub 2014 Jul 11.
Screening tools in older cancer patients TF
February 10, 2015
L. Decoster, K. Van Puyvelde, S. Mohile, U. Wedding, U. Basso, G. Colloca, S. Rostoft, J. Overcash, H. Wildiers, C. Steer, G. Kimmick, R. Kanesvaran, A. Luciani, C. Terret, A. Hurria, C. Kenis, R. Audisio & M. Extermann. Ann Oncol. 2015 Feb;26(2):288-300. doi: 10.1093/annonc/mdu210. Epub 2014 Jun 16.
Prostate Cancer in Senior Adults TF
August 14, 2014
Droz JP, Aapro M, Balducci L, Boyle H4, Van den Broeck T, Cathcart P, Dickinson L, Efstathiou E, Emberton M, Fitzpatrick JM, Heidenreich A, Hughes S, Joniau S, Kattan M, Mottet N, Oudard S, Payne H, Saad F, Sugihara T. Lancet Oncol. 2014 Aug;15(9):e404-e414. doi: 10.1016/S1470-2045(14)70018-X.
Radiotherapy TF
March 13, 2014
Kunkler IH, Audisio R, Belkacemi Y, Betz M, Gore E, Hoffe S, Kirova Y, Koper P, Lagrange JL, Markouizou A, Pfeffer R, Villa S; On behalf of the SIOG Radiotherapy Task Force. Ann Oncol(2014) doi:10.1093/annonc/mdu104
Radiotherapy TF
July 15, 2014
Pallis AG, Gridelli C, Wedding U, Faivre-Finn C, Veronesi G, Jaklitsch M, Luciani A, O'Brien M. Ann Oncol. 2014 Jul;25(7):1270-83. doi: 10.1093/annonc/mdu022. Epub 2014 Mar 16.
Anaesthesia in the Elderly TF
February 24, 2012
Kristjansson SR, Spies C, Veering BTH, et al. J Ger Oncol 2012;3:147-62
Breast Cancer in the Elderly TF
April 12, 2012
Biganzoli L, Wildiers H, Oakman C, et al. Lancet Oncol 2012 Apr;13:e148-60
Anthracyclines in the Elderly TF
October 18, 2010
Aapro M, Bernard-Marty C, Brain E, Batist G, Erdkamp F, Krzemieniecki K, Leonard R, Lluch A, Monfardini S, Ryberg M, Soubeyran P, Wedding U. Ann Oncol. 2011;22:257-67 (Update in progress)
Prostate Cancer in Senior Adults TF
January 15, 2010
Droz JP, et al. Crit Rev Oncol Hematol 2010; 73: 68-91
Prostate Cancer in Senior Adults TF
August 15, 2010
Droz JP, Balducci L, Bolla M, Emberton M, Fitzpatrick JM, Joniau S, Kattan MW, Monfardini S, Moul JW, Naeim A, van Poppel H, Saad F, Sternberg CN. BJU Int 2010;106:462-9
Colorectal Cancer in the Elderly TF
October 15, 2008
Papamichael D, et al. Ann Oncol 2009; 20: 5-16
Metastatic Renal Cell Cancer (mRCC) in the Elderly TF
January 15, 2009
Bellmunt J, et al. Crit Rev Oncol Hematol 2009; 69: 64-72
Surgery in the Elderly TF
February 10, 2008
Audisio R, PACE study participants et al Crit Rev Oncol Hematol 2008; 65: 156-63
Breast Cancer in the Elderly TF
December 8, 2007
Wildiers H, et al. Lancet Oncol 2007; 8:1101-15
Chemotherapy Toxicity in the Elderly TF
May 10, 2007
Lichtman SM et al. J Clin Oncol 2007; 25: 1832-43
Bisphosphonates in the Elderly TF
March 12, 2007
Body JJ, et al. Eur J Cancer 2007; 43: 852-58
Renal Safety in the Elderly TF
August 10, 2007
Launay-Vacher V, et al. Ann Oncol 2007; 18:1314-31
Renal Safety in the Elderly TF
January 20, 2007
Lichtman SM, et al. Eur J Cancer 2007; 43: 14-34
Organization of the Clinical Activity of Geriatric Oncology TF
April 30, 2007
Monfardini S, et al. Crit Rev Oncol Hematol 2007; 62:62-73
Cultural Competence in the Elderly TF
April 15, 2007
Surbone A, et al. Ann Oncol 2007; 18: 633-8
Comprehensive Geriatric Assessment (CGA) TF
September 30, 2005
Extermann M, et al. Crit Rev Oncol Hematol 2005; 55: 241-52 (update in progress)
Surgery in the Elderly TF
May 5, 2004
Audisio RA, et Eur J Cancer 2004; 40: 926-38
Diffuse large B-cell lymphoma
January 29, 2015
Morrison VA, Hamlin P, Soubeyran P, Stauder R, Wadhwa P, Aapro M, Lichtman SM.
Ann Oncol. 2015 Jun;26(6):1058-68. doi: 10.1093/annonc/mdv018. Epub 2015 Jan 29.